Prevalence and Pattern of Substance Abuse among 18 to 60 years Male in a Rural Area of District Etawah, Uttar Pradesh

Abstract: Adolescent and young people’s behavior is of major concern due to Substance abuse. According to WHO, Substance abuse is consistently or sporadic drug use inconsistent with or unrelated to acceptable medical practice. Globally, alcohol and tobacco as a risk factors cause 4.0% and 4.1% of the overall burden of disability respectively. Objective: To determine the prevalence of substance abuse among 18 to 60 years’ male in rural Etawah and to identify type and pattern of substance abuse. Material and Methods: It was a community based cross sectional study carried out in five block of district Etawah for a period of one and half year. 1500 participants were interviewed using pre designed pre-tested questionnaire and data regarding socio demographic profile and pattern of abuse were collected. Data was entered in Microsoft excel sheet and analyzed by SPSS version 24 using appropriate statistical test. Result: Among 1500 participants, majority were below 30 years of age (i.e. 42.8%). In this study prevalence of Substance use among was 47% [707/1500]. Among all the other substance use, smokeless tobacco showed highest prevalence. Conclusion: Substance use is common in both urban as well as in rural area. So there is a need to educate and aware people regarding bad effects of drug abuse

Incidence and Determinants of Low birth weight babies at rural tertiary care hospital in central Uttar Pradesh

Background: An infant’s birth weight is a reliable index of intrauterine growth and a sensitive predictor of newborn chances of survival, growth and long-term physical and psychosocial development. Low birth weight has been defined as birth weight <2.5 kg regardless of gestational age. The incidence of low birth weight (LBW) in India varies between 25–30% and of which 60–65% are because of intrauterine growth retardation. Aim & Objective: To determine the incidence and various determinants of low birth weight among babies delivered at rural tertiary care hospitals in central Uttar Pradesh. Methods and Material: The study was conducted at UPUMS, Saifai, Etawah, among pregnant women who delivered babies from 1st January 2018 to 31st December 2018. Details regarding age of the mother, gravida, parity, gestation period, presence of complications, the procedure for delivery and birth weight of the newborn were recorded and analyzed using SPSS software (version 23)   Results: A total of 7615 deliveries were conducted (53.2% were males, 46.8% were females). The mean birth weight of babies was 2.65 Kg with S.D ± 0.52. Preterm babies were 32% while 67% were term babies and 23% of babies were low birth weight. There was a statistically significant association between birth weight of babies and factors like age of mother, parity of mother, gestation period, and presence of complications during the antenatal period. Conclusions: Prompt identification of high-risk factors, prevention of premature delivery, increasing the use of health services during pregnancy and management of the risk factors would reduce the incidence of low birth weight

Evaluation of NS1, IgM ELISA and RT-PCR in diagnosis of dengue fever

Background: Dengue fever is a mosquito borne disease caused by flavivirus. Its cases are increasing in India with increasing mortality rate year by year hence, prompt and accurate diagnosis is necessary to prevent morbidity and mortality.Methods: In this study we enrolled 125 clinically suspected cases of dengue. All the collected samples were processed for RT-PCR, NS1 and IgM ELISA. We evaluated NS1 antigen ELISA alone, and combination of NS1 and IgM ELISA against RT-PCR.Results: Among 125 clinically suspected case 67 were positive by RT-PCR and 58 were negative. Sensitivity and Specificity of NS1 ELISA and NS1 with IgM ELISA (in combination) against RT-PCR were 83.58%, 94.82% and 95.55%, 79.31% respectively. (p<0.001).Conclusions: The NS1 ELISA alone was sufficient to detect acute phase of dengue fever, although, combination of NS1 and IgM proved to be most appropriate method for detection of acute as well as late phase of dengue fever

Dihydroxyadenine stone with adenine phosphoribosyltransferase deficiency: A case report

Adenine phosphoribosyltransferase (APRT) deficiency is a rare autosomal recessive error of purine metabolism resulting in the generation of 2,8-dihydroxyadenine (DHA), a highly insoluble metabolite of adenine, which can cause radiolucent urolithiasis. This is the second case of DHA stone being reported in India and the first case in India to document the mutation of the APRT gene on blood DNA analysis

A study of Substance Abuse and Quality of Life among Street Children in District Etawah

Background: The research series on street children are carried out in major cities by neglecting the rapidly developing small cities experiencing widespread urbanization. Unfortunately, there is lack of research-based evidences in field of mental health status and quality of life of street children. Aim & Objective: The study aimed to study the pattern of substance abuse & their correlates among street children and to assess the ‘quality of life’ among street children. Material & Methods: A sample of 145 street children of 13-18 years were enrolled by purposive sampling from January 2017 - June 2018 in Market places, Railway station, Bus depot etc. Subjects were searched at known hotspots in Etawah, and further sample was covered using snowball sampling. Information was gathered using predesigned and pre-structured questionnaire, along with WHOQOLBREF and Adolescent Alcohol and Drug Involvement Scale questionnaire. Results: Average Quality of life was tested using t test and ANOVA. Most of the street children 55% were aged between 13-15 years, 65 % had attended school for at least one year. Quality of life showed higher Physical health. Street living children had less psychological health score (30.3±7.1). Prevalence of drug abuse was 54%, while tobacco, alcohol, marijuana, inhalants, were the drugs consumed. Conclusion: Psychological health was more affected. Tobacco & alcohol were the common drugs consumed

Medical School and Stress: A Cross-sectional Study of Stress among Medical Students in Uttar Pradesh University of Medical Sciences in district Etawah

Background: Medical education has come long way since the era of Hippocrates. It is progressively evolving into a more organized and complicated system. All over the world, Medical education is criticized as one of the most demanding and stressful academics, showing effects on physical and mental health of medical students. This research was conducted to study stress and its factors in students of UPUMS, Saifai, Etawah, Uttar Pradesh. Aim & Objectives: To estimate the prevalence of stress among medical students of UPUMS. To estimate internal consistency of Medical Students Stress Questionnaire (MSSQ-40). Material & Methods: A Cross-sectional study was carried out during Oct. 2017 - Mar. 2018 among MBBS Students of all academic years in Uttar Pradesh University of Medical Sciences (UPUMS), Saifai. All the students enrolled in the university available on the day of data collection were recruited in the study. MSSQ-40 was the study tool to assess stress. Ethical clearance was obtained from Ethical Committee. Statistical analysis done in SPSS-23. Results: The mean age of subjects was 22.4±2.3 years, more than 84% of the respondents had moderate and high stress. More number of females perceived stress than the male, 33% female were suffering from high & severe stress. statistically significant. Conclusion: Gender & grades had clear association with stress, academics & interpersonal relation caused more stress. Early detection and effective intervention can prevent future illness among medical students

Future internets escape the simulator

Standardization of basic underlying protocols such as the Internet Protocol (IP) has enabled rapid growth and widespread adoption of the global Internet. However, standardization carries the attendant risks of reducing variability and slowing the pace of progress. Validation and deployment of potential innovations by researchers in networking, distributed computing, and cloud computing are often hampered by Internet ossification, the inertia associated with the accumulated mass of hardware, software, and protocols that constitute the global, public Internet. Researchers simply cannot develop, test, and deploy certain classes of important innovations into the Internet. In the best case, the experimental components and traffic would be ignored; in the worst case, they could disrupt the correct behavior of the Internet. Cloud computing researchers confront a similar dilemma. In order to maintain uniformity and efficiency in their data centers, commercial cloud providers generally do not provide “under the hood” controls that permit modification to the underlying network topology or protocols that comprise the cloud environment